Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911001 | 0.88 | ALDH1A1 (0.51) | KDM4EALDH1A1TDP1HRH3MEN1 | |
| SCHEMBL18905485 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HRH3SMN1; SMN2CYP3A4PSMB1 | |
| SCHEMBL18905502 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HRH3SMN1; SMN2CYP3A4PSMB1 | |
| SCHEMBL18905500 | 0.80 | HRH3 (0.56) | KDM4EALDH1A1HRH3SMN1; SMN2CYP3A4 | |
| SCHEMBL18905419 | 0.78 | KCNH2 (0.36) | SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL14804859 | 0.71 | TSHR (0.44) | KDM4EALDH1A1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL18905423 | 0.71 | CHRM3 (0.34) | SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL873678 | 0.70 | CYP2C19 (0.46) | ALDH1A1SMN1; SMN2CYP3A4MEN1KMT2A | |
| SCHEMBL18905369 | 0.70 | MEN1 (0.41) | TDP1SMN1; SMN2PSMB1PSMB5MEN1 | |
| SCHEMBL18910998 | 0.70 | ALDH1A1 (0.63) | ALDH1A1HRH3SMN1; SMN2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |