Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24533728 | 0.86 | HRH3 (0.61) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL9476152 | 0.85 | HRH3 (0.59) | HRH3SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL18905485 | 0.84 | ALDH1A1 (0.46) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL18905502 | 0.83 | ALDH1A1 (0.54) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL18905283 | 0.82 | HRH3 (0.49) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL21483751 | 0.81 | HRH3 (0.56) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL24533712 | 0.81 | HRH3 (0.55) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL19687568 | 0.81 | SMN1; SMN2 (0.66) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL18905488 | 0.80 | KDM4E (0.41) | HRH3SMN1; SMN2CYP3A4PSMB1PSMB5 | |
| SCHEMBL25575420 | 0.77 | HRH3 (0.52) | HRH3ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |