SCHEMBL189055

SCHEMBL189055

CO[Si](C)(CNN)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554658 0.75
SCHEMBL57193 0.73
SCHEMBL189468 0.73
SCHEMBL1104520 0.72
SCHEMBL975755 0.69 CA12 (0.41)
SCHEMBL686392 0.69 ALOX15 (0.32)
SCHEMBL57590 0.69 TP53 (0.37)
SCHEMBL3884640 0.67
SCHEMBL2460035 0.67 TSHR (0.35)
SCHEMBL12794815 0.66 CA12 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010588-B1 Organosilicon polyurea polymers, elastomers manufactured therefrom and their use HENKEL AG & CO KGAA (DE) 2012-01-04 EP claimed
EP-2010588-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME Henkel AG & Co. KGaA (DE) 2009-01-07 EP claimed
WO-2007118880-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME HENKEL AG & CO. KGAA (DE) 2007-10-25 WO claimed
EP-2010588-B1 Organosilicon polyurea polymers, elastomers manufactured therefrom and their use HENKEL AG & CO KGAA (DE) 2012-01-04 EP disclosed
US-20090099291-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME HENKEL AG & CO KGAA (DE) 2009-04-16 US disclosed
EP-2010588-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME Henkel AG & Co. KGaA (DE) 2009-01-07 EP disclosed
WO-2007118880-A1 ORGANOSILICON-POLYUREA BASE POLYMER, ELASTOMER PREPARED THEREFROM, PREPARATION THEREOF AND USE OF THE SAME HENKEL AG & CO. KGAA (DE) 2007-10-25 WO disclosed