SCHEMBL18905752

SCHEMBL18905752

Fc1ccc(-c2ccc3c4c(cccc24)-c2c-3c(-c3ccccc3)c3ccccc3c2-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 3/20 0.44
NR4A2 P43354 1/20 0.42
ACHE P22303 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
GPR84 Q9NQS5 1/20 0.37
PTGS2 P35354 2/20 0.36
PTGS1 P23219 1/20 0.36
TOP1 P11387 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14226899 1.00 ENPP1 (0.44) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL13492559 0.98 ENPP1 (0.43) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL12032206 0.95 ENPP1 (0.42) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL12032208 0.92 ENPP1 (0.42) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL12032207 0.92 ENPP1 (0.42) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL14226908 0.91 ENPP1 (0.38) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL4076119 0.90 ENPP1 (0.42) ENPP1ACHEHPGDL3MBTL1CRHBP
SCHEMBL16483319 0.89 TOP1 (0.45) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL13932351 0.88 ACHE (0.45) ENPP1NR4A2ACHECYP1A2CYP3A4
SCHEMBL13492554 0.88 ENPP1 (0.37) ENPP1NR4A2CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522137-B2 Organic light emitting element, display device, image information processing device, lighting device, image forming device, exposure device, and organic photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2022-12-06 US disclosed
US-10403827-B2 2,2′-bibenzo[D]imidazolidene compound having condensed rings at the 1-, 1′-, 3- and 3′-positions, and organic light-emitting element, display device, image information processing apparatus, lighting device, image forming apparatus and exposure unit, each containing the same CANON KABUSHIKI KAISHA (JP) 2019-09-03 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-9882148-B2 Organic compound, field element, organic light-emitting element, display apparatus, image information-processing apparatus, lighting apparatus, image-forming apparatus, and exposure apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-30 US disclosed
US-9882148-B2 Organic compound, field element, organic light-emitting element, display apparatus, image information-processing apparatus, lighting apparatus, image-forming apparatus, and exposure apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-30 US disclosed
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170155059-A1 ORGANIC COMPOUND, FIELD ELEMENT, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION-PROCESSING APPARATUS, LIGHTING APPARATUS, IMAGE-FORMING APPARATUS, AND EXPOSURE APPARATUS SCO2, OGFOD1, OXER1 ENPP1 3982/4885NR4A2 1240/4885ACHE 3707/4885
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME GRK1, BRD1, BRD8 ENPP1 4211/4885NR4A2 687/4885ACHE 3821/4885
US-11522137-B2 Organic light emitting element, display device, image information processing device, lighting device, image forming device, exposure device, and organic photoelectric conversion element AHR, CYP1A1, CYP1B1 ENPP1 3123/4885NR4A2 61/4885ACHE 2473/4885
US-10403827-B2 2,2′-bibenzo[D]imidazolidene compound having condensed rings at the 1-, 1′-, 3- and 3′-positions, and organic light-emitting element, display device, image information processing apparatus, lighting device, image forming apparatus and exposure unit, each containing the same GRK1, BRD1, BRD8 ENPP1 4161/4885NR4A2 686/4885ACHE 3834/4885
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 ENPP1 3304/4885NR4A2 45/4885ACHE 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.