SCHEMBL18906007

SCHEMBL18906007

CC(N)c1ccc(NC(=O)c2ccco2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 13/20 0.71
NPC1 O15118 11/20 0.71
SMN1; SMN2 Q16637 7/20 0.66
TP53 P04637 7/20 0.66
GAA P10253 3/20 0.66
PTPN2 P17706 1/20 0.65
PTPN1 P18031 1/20 0.65
PTPN6 P29350 1/20 0.65
PTPN11 Q06124 1/20 0.65
KMT2A Q03164 5/20 0.61
MEN1 O00255 4/20 0.61
MAPT P10636 2/20 0.60
GFER P55789 1/20 0.60
APOBEC3G Q9HC16 1/20 0.59
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
KDM4E B2RXH2 2/20 0.57
HSD17B10 Q99714 1/20 0.57
PKM P14618 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17660221 0.88 RAB9A (0.74) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL5999016 0.84 PTPN2 (0.63) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL4756677 0.83 RAB9A (0.64) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL7716927 0.80 PTPN2 (0.75) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL1846669 0.80 RAB9A (0.83) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL22823075 0.80 RAB9A (1.00) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL8244859 0.79 RAB9A (0.67) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL6637453 0.78 PTPN2 (0.77) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL2997673 0.77 RAB9A (1.00) RAB9ANPC1SMN1; SMN2TP53GAA
SCHEMBL18906008 0.77 PTPN2 (0.71) RAB9ANPC1SMN1; SMN2TP53GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed