SCHEMBL2997673

SCHEMBL2997673

O=C(Nc1ccccc1)c1ccco1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 1.00
SMN1; SMN2 Q16637 4/20 0.87
NPC1 O15118 4/20 0.87
KMT2A Q03164 4/20 0.87
TP53 P04637 3/20 0.87
MEN1 O00255 3/20 0.87
MAPT P10636 2/20 0.87
GFER P55789 1/20 0.87
PTPN2 P17706 1/20 0.77
PTPN1 P18031 1/20 0.77
PTPN6 P29350 1/20 0.77
PTPN11 Q06124 1/20 0.77
LMNA P02545 1/20 0.73
KCNK3 O14649 1/20 0.73
KCNK9 Q9NPC2 1/20 0.73
GAA P10253 1/20 0.72
BLM P54132 1/20 0.69
CYP2C9 P11712 1/20 0.69
ALDH1A1 P00352 3/20 0.66
MAPK1 P28482 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31228945 0.98 RAB9A (0.96) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL31401954 0.93 RAB9A (0.87) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL7662848 0.90 RAB9A (0.81) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL23011774 0.87 ALDH1A1 (0.84) RAB9ASMN1; SMN2NPC1KMT2AMEN1
SCHEMBL7743467 0.86 RAB9A (0.75) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL15056399 0.86 RAB9A (0.75) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL6637453 0.85 PTPN2 (0.77) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL13219577 0.84 PTPN2 (0.79) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL6633899 0.84 PTPN2 (0.75) RAB9ASMN1; SMN2NPC1KMT2ATP53
SCHEMBL7743465 0.84 PTPN2 (0.75) RAB9ASMN1; SMN2NPC1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023212494-A2 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-11-02 WO claimed
EP-4255175-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE Pioneer Hi-Bred International, Inc. (US) 2023-10-11 EP claimed
WO-2022166842-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF 山东康乔生物科技有限公司 2022-08-11 WO claimed
WO-2022099169-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-05-12 WO claimed
CN-113973845-A Compositions and methods for controlling plant disease 农业生物群落股份有限公司 2022-01-28 CN claimed
CN-108358511-A A kind of efficient soil-solidified-agent and preparation method thereof 浙江乔兴建设集团有限公司 2018-08-03 CN claimed
CN-108191310-A A kind of solidified earth and the antifouling impervious processing method of big type coal field 中冶东方工程技术有限公司 2018-06-22 CN claimed
CN-105367010-A Hardening agent for road and roadbed hardening method ZHENG WEIZHONG 2016-03-02 CN claimed
US-20080064876-A1 Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione CELGENE CORPORATION 2008-03-13 US claimed
WO-2007136640-A2 PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE CELGENE CORPORATION (US) 2007-11-29 WO claimed
EP-0795596-B1 Fuel compositions SHELL INT RESEARCH (NL) 2000-10-11 EP claimed
US-20260144256-A1 OXALOACETATE AND RELATED COMPOUNDS AS HERBICIDAL AGENTS VERDESIAN LIFE SCIENCES U.S., LLC (US) 2026-05-28 US disclosed
EP-3340799-B1 COMPOSITIONS AND METHODS FOR CONTROLLING PLANT DISEASE CERTIS USA LLC (US) 2026-05-27 EP disclosed
EP-4058531-B1 SOIL WETTER COMPOSITION CRODA INT PLC (GB) 2026-05-20 EP disclosed
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 US disclosed
US-3959258-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3948633-A 3,5-Dimethyl-2-thienylcarboxanilide and 3,5-dimethyl-2-thienyl-(N-haloalkylthiocarboxanilide) herbicides CHEVRON RESEARCH COMPANY (US) 1976-04-06 US disclosed
US-3939149-A BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed
US-3936442-A ANTIBIOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed
US-3933795-A Ureidoacetamido-penicillins Konig, Hans-Bodo (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144256-A1 OXALOACETATE AND RELATED COMPOUNDS AS HERBICIDAL AGENTS SLC6A12, SLC6A5, CA2 RAB9A 4144/4885SMN1; SMN2 4406/4885NPC1 2442/4885
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC RAB9A 2401/4885SMN1; SMN2 3133/4885NPC1 2742/4885
US-20080064876-A1 Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione TNF, DHPS, IDO1 RAB9A 3356/4885SMN1; SMN2 2108/4885NPC1 3122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.