SCHEMBL18906153

SCHEMBL18906153

COC(=O)c1cccc2cc(O)c(O)cc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
TSHR P16473 1/20 0.55
KMT2A Q03164 2/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 1/20 0.51
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CA1 P00915 5/20 0.48
CA2 P00918 5/20 0.48
CA9 Q16790 5/20 0.48
CA12 O43570 4/20 0.48
CA7 P43166 4/20 0.48
CA14 Q9ULX7 4/20 0.48
GAA P10253 2/20 0.47
POLB P06746 1/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47
MPL P40238 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19733167 0.89 ALDH1A1 (0.56) LMNATSHRKMT2AMAPTMEN1
SCHEMBL6953102 0.88 LMNA (0.58) LMNATSHRKMT2AMAPTMEN1
SCHEMBL29403597 0.87 ALDH1A1 (0.54) LMNATSHRKMT2AMAPTMEN1
SCHEMBL6761980 0.87 ALDH1A1 (0.54) LMNATSHRKMT2AMAPTMEN1
SCHEMBL27370762 0.87 KDM4E (0.50) LMNATSHRKMT2AMAPTMEN1
SCHEMBL1164706 0.84 ALDH1A1 (0.61) LMNATSHRKMT2AMAPTMEN1
SCHEMBL25189907 0.83 ALDH1A1 (0.59) LMNATSHRKMT2AMAPTMEN1
SCHEMBL27398809 0.83 ALDH1A1 (0.50) LMNATSHRKMT2AMAPTMEN1
SCHEMBL30571222 0.81 CA12 (0.54) LMNATSHRKMT2AMAPTMEN1
SCHEMBL273978 0.81 CA12 (0.54) LMNATSHRKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153547-A1 COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-01 US disclosed