SCHEMBL18906949

SCHEMBL18906949

C=C(C)C(=O)N(CCN(CCS(=O)(=O)O)C(=O)C(=C)C)CCS(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.31
PDE4A P27815 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A6 P31641 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3342370 0.88 APP (0.35)
SCHEMBL15631777 0.84
SCHEMBL27455553 0.82 APP (0.31)
SCHEMBL8763042 0.82 PTGS1 (0.30) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL742679 0.81 USP2 (0.33) LMNA
Ammonia Solution, Strong SCHEMBL18139365 0.80
SCHEMBL19547658 0.79 THRB (0.33) LMNA
SCHEMBL18906952 0.78 GRIN2D (0.38)
SCHEMBL19220237 0.77
SCHEMBL11964294 0.73 HSD11B1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005856-B2 Curable composition FUJIFILM CORPORATION (JP) 2018-06-26 US disclosed
US-20170152331-A1 CURABLE COMPOSITION, FUNCTIONAL POLYMER HARDENED PRODUCT, STACK OR DEVICE COMPRISING FUNCTIONAL POLYMER MEMBRANE, AMIDE COMPOUND, AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2017-06-01 US disclosed
US-20170152331-A1 CURABLE COMPOSITION, FUNCTIONAL POLYMER HARDENED PRODUCT, STACK OR DEVICE COMPRISING FUNCTIONAL POLYMER MEMBRANE, AMIDE COMPOUND, AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152331-A1 CURABLE COMPOSITION, FUNCTIONAL POLYMER HARDENED PRODUCT, STACK OR DEVICE COMPRISING FUNCTIONAL POLYMER MEMBRANE, AMIDE COMPOUND, AND MANUFACTURING METHOD THEREOF ASH2L, VMA21, SGMS1 PTGS1 1781/4885PDE4A 4739/4885LMNA 2640/4885
US-10005856-B2 Curable composition ASH2L, ASH1L, CHRM1 PTGS1 2414/4885PDE4A 4806/4885LMNA 2217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.