Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909761 | 0.92 | USP2 (0.39) | TAS1R3TAS1R1USP2SMN1; SMN2KDM4E | |
| SCHEMBL18971798 | 0.89 | SMN1; SMN2 (0.39) | TAS1R3TAS1R1USP2SMN1; SMN2KDM4E | |
| SCHEMBL19361582 | 0.85 | USP2 (0.39) | USP2SMN1; SMN2KDM4EHTR2AHTR2C | |
| SCHEMBL18909760 | 0.85 | KCNH2 (0.39) | TAS1R3TAS1R1USP2SMN1; SMN2KDM4E | |
| SCHEMBL18909756 | 0.85 | KDM4E (0.38) | TAS1R3TAS1R1USP2SMN1; SMN2KDM4E | |
| SCHEMBL18907024 | 0.84 | USP2 (0.38) | TAS1R3TAS1R1USP2SMN1; SMN2KDM4E | |
| SCHEMBL18907014 | 0.81 | USP2 (0.41) | USP2SMN1; SMN2KDM4EHTR2AHTR2C | |
| SCHEMBL21231886 | 0.80 | TAS1R3 (0.39) | TAS1R3TAS1R1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL18909753 | 0.79 | TAS1R3 (0.39) | TAS1R3TAS1R1KDM4EHTR2AHTR2C | |
| SCHEMBL21231883 | 0.79 | PGR (0.40) | TAS1R3TAS1R1KDM4EHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091617-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |