SCHEMBL18907237

SCHEMBL18907237

CCc1ccc2c(ccc3c2c(CC)nc2ccc4ccccc4c23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP2A6 P11509 1/20 0.47
TYMS P04818 3/20 0.41
HPGD P15428 5/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
KIF11 P52732 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
AKR1B1 P15121 1/20 0.37
LMNA P02545 2/20 0.36
AHR P35869 1/20 0.36
ATM Q13315 2/20 0.36
GAA P10253 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18907182 0.85 CYP1A2 (0.50) CYP1A2CYP2A6TYMSHPGDALDH1A1
SCHEMBL18907186 0.83 CYP1A2 (0.47) CYP1A2CYP2A6TYMSHPGDALDH1A1
SCHEMBL18907233 0.83 CYP1A2 (0.51) CYP1A2CYP2A6TYMSHPGDALDH1A1
SCHEMBL598696 0.78 CYP1A2 (0.69) CYP1A2CYP2A6HPGDALDH1A1MAPT
SCHEMBL19009455 0.77 POLB (0.45) HPGDALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL7773085 0.77 CYP1A2 (0.67) CYP1A2CYP2A6HPGDALDH1A1MAPT
SCHEMBL18748054 0.76 CYP1A2 (0.39) CYP1A2CYP2A6TYMSMAPTKIF11
SCHEMBL9765522 0.72 AKR1B1 (0.64) CYP1A2CYP2A6HPGDALDH1A1MAPT
SCHEMBL17036576 0.71 POLB (0.49) TYMSHPGDALDH1A1KDM4EL3MBTL1
SCHEMBL18748051 0.71 KDM4E (0.36) CYP1A2CYP2A6ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170155057-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170155057-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, OCIAD1, CCNT1 CYP1A2 421/4885CYP2A6 2320/4885TYMS 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.