Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 6/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 5/20 | 0.33 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18821193 | 0.93 | KDM4E (0.33) | PPARG | |
| SCHEMBL18907920 | 0.86 | PTGDR2 (0.34) | PTGDR2AKR1C3CYSLTR2CYSLTR1PPARG | |
| SCHEMBL18907913 | 0.81 | CNR2 (0.37) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL18821417 | 0.80 | PPARG (0.37) | CYSLTR2CYSLTR1PPARGP2RY10GPR174 | |
| SCHEMBL18821243 | 0.79 | NR3C2 (0.36) | — | |
| SCHEMBL18907696 | 0.77 | FAAH (0.38) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL18821192 | 0.77 | NR3C2 (0.36) | — | |
| SCHEMBL18820728 | 0.77 | NR3C2 (0.36) | — | |
| SCHEMBL18883374 | 0.76 | ACACB (0.32) | — | |
| SCHEMBL18972304 | 0.75 | SLC6A9 (0.43) | AKR1C3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091617-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |