SCHEMBL18909070

SCHEMBL18909070

CCCCc1cc(O)c2c(c1)OC(C)(C)C1CCC(C)=CC21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 1.00
CNR1 P21554 12/20 1.00
ABHD12 Q8N2K0 3/20 0.94
ABHD6 Q9BV23 3/20 0.94
FAAH O00519 2/20 0.94
TRPM8 Q7Z2W7 2/20 0.94
GPR55 Q9Y2T6 2/20 0.94
NR1I2 O75469 1/20 0.94
LDHA P00338 1/20 0.94
GLRA1 P23415 1/20 0.94
GPR183 P32249 1/20 0.94
DRD3 P35462 1/20 0.94
ENPP2 Q13822 1/20 0.94
GPR18 Q14330 1/20 0.94
TRPA1 O75762 1/20 0.88
HTR1A P08908 1/20 0.88
TRPV1 Q8NER1 1/20 0.88
TRPV3 Q8NET8 1/20 0.88
TRPV6 Q9H1D0 1/20 0.88
TRPV4 Q9HBA0 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31545608 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL13214127 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL22705480 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL29422046 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL25098270 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL24351964 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
SCHEMBL29351497 1.00 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
Dronabinol SCHEMBL1227386 0.97 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
Dronabinol SCHEMBL13394311 0.97 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH
Dronabinol SCHEMBL24702729 0.97 CNR2 (1.00) CNR2CNR1ABHD12ABHD6FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230375561-A1 METHODS FOR IDENTIFICATION, STRATIFICATION, AND TREATMENT OF CNS DISEASES KADDURAH DAOUK RIMA F (US) 2023-11-23 US disclosed
US-20230375561-A1 METHODS FOR IDENTIFICATION, STRATIFICATION, AND TREATMENT OF CNS DISEASES KADDURAH DAOUK RIMA F (US) 2023-11-23 US disclosed
US-20230340555-A1 PRODUCTION OF GLYCOSYLATED CANNABINOIDS WILLOW BIOSCIENCES, INC. (CA) 2023-10-26 US disclosed
WO-2023205404-A2 BIOSYNTHESIS OF CYCLOLAVANDULYL DERIVATIVES OF AROMATIC COMPOUNDS INVIZYNE TECHNOLOGIES, INC. (US) 2023-10-26 WO disclosed
EP-4244371-A1 PRODUCTION OF CANNABINOIDS/PHYTOCANNABINOIDS WITH A PLANT EXTRACT Technische Universität Darmstadt (DE) 2023-09-20 EP disclosed
US-20230279449-A1 COMPOSITIONS AND METHODS FOR ENHANCING RECOMBINANT BIOSYNTHESIS OF CANNABINOIDS WILLOW BIOSCIENCES, INC. (CA) 2023-09-07 US disclosed
WO-2023133483-A1 RECOMBINANT POLYPEPTIDES WITH BERBERINE BRIDGE ENZYME ACTIVITY USEFUL FOR THE BIOSYNTHESIS OF CANNABINOIDS INVIZYNE TECHNOLOGIES, INC. (US) 2023-07-13 WO disclosed
US-20230193329-A1 Compositions and Methods for Recombinant Biosynthesis of Cannabinoids WILLOW BIOSCIENCES, INC. (CA) 2023-06-22 US disclosed
US-20230193329-A1 Compositions and Methods for Recombinant Biosynthesis of Cannabinoids WILLOW BIOSCIENCES, INC. (CA) 2023-06-22 US disclosed
WO-2023102655-A1 CATALYTIC TETRAHYDROCANNABINOL SYNTHESIS AND PRECURSORS KARE CHEMICAL TECHNOLOGIES INC. (CA) 2023-06-15 WO disclosed
US-11518983-B1 Prenyltransferase variants with increased thermostability INVIZYNE TECHNOLOGIES, INC. (US) 2022-12-06 US disclosed
US-20220186231-A1 RECOMBINANT ACYL ACTIVATING ENZYME (AAE) GENES FOR ENHANCED BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS WILLOW BIOSCIENCES, INC. (CA) 2022-06-16 US disclosed
WO-2022125960-A1 RECOMBINANT ACYL ACTIVATING ENZYME (AAE) GENES FOR ENHANCED BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS WILLOW BIOSCIENCES, INC. (CA) 2022-06-16 WO disclosed
WO-2022101306-A1 PRODUCTION OF CANNABINOIDS/PHYTOCANNABINOIDS WITH A PLANT EXTRACT Technische Universität Darmstadt (DE) 2022-05-19 WO disclosed
WO-2022099078-A1 PRODUCTION OF GLYCOSYLATED CANNABINOIDS WILLOW BIOSCIENCES, INC. (CA) 2022-05-12 WO disclosed
WO-2021222288-A1 COMPOSITIONS AND METHODS FOR ENHANCING RECOMBINANT BIOSYNTHESIS OF CANNABINOIDS WILLOW BIOSCIENCES, INC. (CA) 2021-11-04 WO disclosed
WO-2021195517-A2 COMPOSITIONS AND METHODS FOR RECOMBINANT BIOSYNTHESIS OF CANNABINOIDS WILLOW BIOSCIENCES, INC. (CA) 2021-09-30 WO disclosed
WO-2021163023-A1 STABLE FORMULATIONS OF DRONABINOL TRYAGx Labs Inc. (US) 2021-08-19 WO disclosed
US-20210251947-A1 STABLE FORMULATIONS OF DRONABINOL TRYAGx Labs Inc. 2021-08-19 US disclosed
WO-2017091764-A1 CANNABIS OIL COMPOSITIONS AND METHODS FOR PREPARATION THEREOF CONSTANCE THERAPEUTICS, INC. (US) 2017-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210251947-A1 STABLE FORMULATIONS OF DRONABINOL CNR2, CNR1, GPR18 CNR2 1/4885CNR1 2/4885ABHD12 1201/4885
US-20230375561-A1 METHODS FOR IDENTIFICATION, STRATIFICATION, AND TREATMENT OF CNS DISEASES SLC25A20, CPT2, NDUFAB1 CNR2 91/4885CNR1 106/4885ABHD12 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.