SCHEMBL18909186

SCHEMBL18909186

Nc1nc2c(ccc3scnc32)s1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
PDPK1 O15530 1/20 0.46
PDE10A Q9Y233 1/20 0.46
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HSD17B10 Q99714 1/20 0.38
NSD1 Q96L73 1/20 0.36
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
AXL P30530 1/20 0.34
GFER P55789 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CG P48736 2/20 0.34
DYRK1A Q13627 1/20 0.34
PIK3CA P42336 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6118333 0.83 SMN1; SMN2 (0.59) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A
SCHEMBL5160632 0.78 ALDH1A1 (0.46) ALDH1A1TDP1HSD17B10RAB9AL3MBTL1
SCHEMBL19214675 0.77 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL16438237 0.77 NPC1 (0.45) ALDH1A1LMNASMN1; SMN2HSD17B10MAPT
SCHEMBL15880357 0.77 ALDH1A1 (0.41) ALDH1A1LMNASMN1; SMN2CYP3A4HSD17B10
SCHEMBL18309107 0.73 ACACB (0.37)
SCHEMBL19730978 0.73 NPC1 (0.43) ALDH1A1LMNATDP1MAPTRAB9A
SCHEMBL17281511 0.73 ALDH1A1 (0.53) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A
SCHEMBL15880672 0.72 ALDH1A1 (0.58) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A
Benzo[D]Thiazole SCHEMBL7787147 0.71 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2PDPK1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423455-B1 SEMICONDUCTING POLYMER CLAP CO LTD (KR) 2021-06-23 EP disclosed
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed
EP-3464415-B1 SEMICONDUCTORS BASF SE (DE) 2020-08-19 EP disclosed
WO-2020078815-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS BASF SE (DE) 2020-04-23 WO disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
WO-2018104367-A2 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2018-06-14 WO disclosed
WO-2017202635-A1 SEMICONDUCTORS BASF SE (DE) 2017-11-30 WO disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed
WO-2017089952-A1 DEGRADABLE CONJUGATED POLYMERS The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel (US) 2017-06-01 WO disclosed