Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzo[D]Thiazole SCHEMBL3112885 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HSD17B10SMN1; SMN2LMNATDP1 | |
| SCHEMBL969167 | 0.82 | ALDH1A1 (0.66) | ALDH1A1HSD17B10SMN1; SMN2PDE10APDPK1 | |
| Hydrochloric Acid SCHEMBL28787382 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HSD17B10SMN1; SMN2PDE10APDPK1 | |
| Benzo[D]Thiazole SCHEMBL28485741 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HSD17B10SMN1; SMN2LMNATDP1 | |
| Benzo[D]Thiazole SCHEMBL18549009 | 0.77 | ALDH1A1 (0.95) | ALDH1A1HSD17B10SMN1; SMN2TDP1KDM4E | |
| Benzo[D]Thiazole SCHEMBL27741535 | 0.75 | ALDH1A1 (0.91) | ALDH1A1HSD17B10SMN1; SMN2TDP1KDM4E | |
| Benzo[D]Thiazole SCHEMBL27404988 | 0.75 | ALDH1A1 (0.91) | ALDH1A1HSD17B10SMN1; SMN2TDP1KDM4E | |
| Benzo[D]Thiazole SCHEMBL27485138 | 0.75 | ALDH1A1 (0.91) | ALDH1A1HSD17B10SMN1; SMN2TDP1KDM4E | |
| Benzo[D]Thiazole SCHEMBL451685 | 0.75 | — | — | |
| Benzo[D]Thiazole SCHEMBL8430 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789723-B1 | POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS | MICHIGAN MOLECULAR INST (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5985969-A | REACTION PRODUCT OF PYROMELLITIC DIANHYDRIDE AND DIAMINO BENZOXAZOLE WITH CHAIN EXTENDERS FOR COATING ON SUBSTRATES | THE DOW CHEMICAL COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| US-5919892-A | CYCLIZED TO POLYIMIDEBENZOXAZOLE | THE DOW CHEMICAL COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5741585-A | Polyamic acid precursors and methods for preparing higher molecular weight polyamic acids and polyimidebenzoxazole | THE DOW CHEMICAL COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0789723-A1 | POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS | THE DOW CHEMICAL COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996013541-A1 | POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS | THE DOW CHEMICAL COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |