Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19275282 | 0.82 | EPHX2 (0.44) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL18909116 | 0.77 | NPC1 (0.44) | EPHX2NPY5RALDH1A1 | |
| SCHEMBL20054243 | 0.76 | HTR2A (0.33) | — | |
| SCHEMBL18909336 | 0.75 | EPHX2 (0.39) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL12516865 | 0.74 | L3MBTL3 (0.53) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL25923427 | 0.74 | EPHX2 (0.42) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL18909244 | 0.73 | EPHX2 (0.49) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL18909251 | 0.73 | EPHX2 (0.45) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL21281128 | 0.73 | EPHX2 (0.49) | EPHX2NPY5REPHX1ALDH1A1 | |
| SCHEMBL21106943 | 0.73 | PIK3CD (0.46) | EPHX2NPY5REPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596072-B1 | PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2022-06-22 | — | — | EP | disclosed |
| WO-2017089390-A1 | JANUS KINASES INHIBITORS, COMPOSITIONS THEREOF AND USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-01 | — | — | WO | disclosed |