Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.50 |
| ▸ | PDE4A | P27815 | 5/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.50 |
| ▸ | ACACB | O00763 | 9/20 | 0.42 |
| ▸ | ACACA | Q13085 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908171 | 0.89 | ACACB (0.44) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL18909759 | 0.86 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL14945398 | 0.85 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL30901794 | 0.85 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL29700513 | 0.85 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL14945397 | 0.85 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL17580347 | 0.85 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL21816549 | 0.85 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL21980409 | 0.85 | ACACB (0.45) | ACACBACACA | |
| SCHEMBL17580298 | 0.85 | ACACB (0.43) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091602-A1 | ESTER ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |
| WO-2017091600-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |