Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 12/20 | 0.47 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | CTSB | P07858 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675931 | 0.83 | CTSL (0.54) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL8218554 | 0.83 | CTSL (0.54) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL20467579 | 0.83 | CTSC (0.53) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL8296697 | 0.82 | CTSC (0.50) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL5512889 | 0.82 | CTSC (0.53) | CTSCCTSLCTSSCTSKCTSB | |
| Hydrochloric Acid SCHEMBL23673462 | 0.82 | CTSL (0.53) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL5520684 | 0.82 | CTSC (0.53) | CTSCCTSLCTSSCTSKCTSB | |
| Hydrochloric Acid SCHEMBL23673461 | 0.82 | CTSL (0.53) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL11889693 | 0.81 | CTSK (0.47) | CTSCCTSLCTSSCTSKCTSB | |
| SCHEMBL347231 | 0.80 | CTSK (0.55) | CTSCCTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017089389-A1 | TRYPANOSOMES INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-01 | — | — | WO | disclosed |