Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.38 |
| ▸ | LPL | P06858 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911047 | 0.90 | OPRL1 (0.41) | OPRL1HSD11B1LPLLIPGTHRB | |
| SCHEMBL7078035 | 0.86 | HSD11B1 (0.40) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL18905472 | 0.83 | HSD11B1 (0.37) | HSD11B1MEN1KMT2A | |
| SCHEMBL18905317 | 0.81 | HSD11B1 (0.35) | HSD11B1MEN1KMT2A | |
| SCHEMBL18911059 | 0.80 | HSD11B1 (0.36) | HSD11B1MEN1KMT2ACNR2 | |
| SCHEMBL6899610 | 0.77 | HSD11B1 (0.54) | HSD11B1MEN1KMT2A | |
| SCHEMBL18910952 | 0.76 | TSHR (0.47) | HSD11B1MEN1KMT2APLK1CNR2 | |
| SCHEMBL18910945 | 0.75 | ALOX5AP (0.38) | OPRM1OPRD1OPRK1OPRL1HSD11B1 | |
| SCHEMBL15179667 | 0.74 | NPSR1 (0.39) | HSD11B1MEN1KMT2A | |
| SCHEMBL18905336 | 0.73 | HSD11B1 (0.33) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |