Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911027 | 0.86 | OPRM1 (0.39) | HSD11B1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL18911059 | 0.82 | HSD11B1 (0.36) | HSD11B1MEN1KMT2ANR1I2 | |
| SCHEMBL6899454 | 0.80 | HSD11B1 (0.39) | HSD11B1SLC5A1SLC5A2 | |
| SCHEMBL6899610 | 0.79 | HSD11B1 (0.54) | HSD11B1MEN1KMT2A | |
| SCHEMBL18905472 | 0.79 | HSD11B1 (0.37) | HSD11B1MEN1KMT2ANR1I2 | |
| SCHEMBL18905317 | 0.77 | HSD11B1 (0.35) | HSD11B1MEN1KMT2ANR1I2 | |
| SCHEMBL15179667 | 0.77 | NPSR1 (0.39) | HSD11B1MEN1KMT2AGAA | |
| SCHEMBL18905336 | 0.76 | HSD11B1 (0.33) | HSD11B1MEN1KMT2ANR1I2 | |
| SCHEMBL18910952 | 0.76 | TSHR (0.47) | HSD11B1MEN1KMT2A | |
| SCHEMBL3024025 | 0.76 | HSD11B1 (0.59) | HSD11B1MEN1KMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |