Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ST6GAL1 | P15907 | 5/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153021 | 0.90 | P2RY2 (0.56) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL26080 | 0.83 | LMNA (0.66) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL26986754 | 0.83 | LMNA (0.66) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL12472103 | 0.82 | LMNA (0.64) | LMNATHRBMTORMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL15663884 | 0.82 | LMNA (0.64) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL17131165 | 0.80 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL18785094 | 0.80 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL18775358 | 0.80 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL18785093 | 0.80 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL15428383 | 0.80 | LMNA (0.59) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670238-B1 | 5′-dibenzyl phosphates of 5-azacytidine or 2′-deoxy-5-azacytidine | OHARA PHARMACEUTICAL CO., LTD. (JP) | 2017-06-06 | — | — | US | disclosed |