SCHEMBL26080

SCHEMBL26080

Nc1ccn([C@@H]2O[C@H](NO)[C@@H](O)[C@H]2O)c(=O)n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.66
THRB P10828 1/20 0.66
MTOR P42345 1/20 0.66
MDM2 Q00987 1/20 0.66
NCOA1 Q15788 1/20 0.66
NCOA3 Q9Y6Q9 1/20 0.66
NT5E P21589 1/20 0.54
P2RY2 P41231 1/20 0.48
PDE3A Q14432 3/20 0.47
CACNA1F O60840 2/20 0.47
ALB P02768 2/20 0.47
MAPT P10636 2/20 0.47
CACNA1D Q01668 2/20 0.47
CACNA1S Q13698 2/20 0.47
CACNA1C Q13936 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PDE4D Q08499 1/20 0.46
SLC29A1 Q99808 1/20 0.46
TSHR P16473 1/20 0.46
GLA P06280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26986754 1.00 LMNA (0.66) LMNATHRBMTORMDM2NCOA1
Hydrochloric Acid SCHEMBL15663884 0.99 LMNA (0.64) LMNATHRBMTORMDM2NCOA1
SCHEMBL12472103 0.90 LMNA (0.64) LMNATHRBMTORMDM2NCOA1
Benzoic Acid SCHEMBL1843659 0.89 LMNA (0.55) LMNATHRBMTORMDM2NCOA1
SCHEMBL18911166 0.83 LMNA (0.56) LMNATHRBMTORMDM2NCOA1
SCHEMBL2835710 0.83 LMNA (0.69) LMNATHRBMTORMDM2NCOA1
SCHEMBL15663551 0.83 LMNA (0.50) LMNATHRBMTORMDM2NCOA1
SCHEMBL4879682 0.82 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL10015791 0.82 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL399323 0.82 LMNA (0.67) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14454 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746876-A1 UDP-GLUCOSE CERAMIDE GLUCOSYLTRANSFERASE SYNTHASE (UGCG) INHIBITORS IN THE TREATMENT OF CANCER Katholieke Universiteit Leuven (BE) 2026-05-27 EP claimed
CN-116209439-B Cereblon protein modulators Saint Jude Children's Research Hospital Ltd. (US) 2026-05-26 CN claimed
CN-122070932-A Application of combination of decitabine and anti-HER 2 antibody in preparation of medicines for treating tumors 上海交通大学 2026-05-22 CN claimed
US-20260137674-A1 COMBINATION THERAPY USING A KRAS G12D INHIBITOR, AND A NUCLEOSIDE ANALOG, AND/OR A MICROTUBULE INHIBITOR INCYTE CORP (US) 2026-05-21 US claimed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
CN-122028920-A Method for treating hematological cancer 丹娜-法伯癌症研究院 2026-05-12 CN claimed
CN-122028934-A Combination of CLDN18_2 antibody and chemotherapeutic drug and application thereof 江苏奥赛康生物医药有限公司 2026-05-12 CN claimed
CN-122004132-A Method for establishing efficient regeneration system of fenugreek 新疆维吾尔自治区药物研究院 2026-05-12 CN claimed
US-20260124190-A1 METHOD FOR TREATING A DISEASE OR CONDITION USING A PYRAZOLE COMPOUND OR FORMULATION THEREOF RIGEL PHARMACEUTICALS, INC. (US) 2026-05-07 US claimed
WO-2026090323-A1 COMBINATION THERAPY USING A KRAS G12D INHIBITOR, AND A NUCLEOSIDE ANALOG, AND/OR A MICROTUBULE INHIBITOR AND ITS USE IN THE TREATMENT OF CANCER INCYTE CORPORATION (US) 2026-04-30 WO claimed
CN-1309180-A Multi-mesoblast pedigree differential potency for stromal cell from fatty tissue, and its use ZEN BIO INC (US) 2001-08-22 CN claimed
US-6106866-A ANTITUMOR AGENTS AND DERMATAN SULFATE ACCESS PHARMACEUTICALS, INC. (US) 2000-08-22 US claimed
EP-0794796-A1 COMPLEXES OF DERMATAN SULFATE AND DRUGS, GIVING IMPROVED PHARMACOKINETICS Access Pharmaceuticals, Inc. (US) 1997-09-17 EP claimed
WO-1996040091-A1 DUAL FUNCTIONAL CYTOTOXIC/RADIOSENSITIZER COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF VIVORX PHARMACEUTICALS, INC. (US) 1996-12-19 WO claimed
WO-1996019242-A1 COMPLEXES OF DERMATAN SULFATE AND DRUGS, GIVING IMPROVED PHARMACOKINETICS ACCESS PHARMACEUTICALS, INC. (US) 1996-06-27 WO claimed
WO-1995028404-A1 7,11 DISUBSTITUTED CAMPTOTHECIN DERIVATIVES, FORMULATIONS CONTAINING SUCH DERIVATIVES AND THEIR USE BIONUMERIK PHARMACEUTICALS, INC. (US) 1995-10-26 WO claimed
EP-0282160-B1 A method of obtaining a retrovirus-containing fraction from retrovirus-containing cells UNIV LIVERPOOL (GB) 1995-05-10 EP claimed
US-5324831-A Phosphoramidite reagent for chemical synthesis of modified DNA THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES (US) 1994-06-28 US claimed
EP-0282160-A2 A method of obtaining a retrovirus-containing fraction from retrovirus-containing cells THE UNIVERSITY OF LIVERPOOL (GB) 1988-09-14 EP claimed
EP-0262696-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1988-04-06 EP claimed