⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061322 | 0.83 | KDM4E (0.71) | — | |
| SCHEMBL22870840 | 0.83 | KDM4E (0.52) | — | |
| SCHEMBL6484888 | 0.78 | — | — | |
| SCHEMBL22446638 | 0.77 | KDM4E (0.62) | — | |
| SCHEMBL21415800 | 0.75 | KDM4E (0.38) | — | |
| SCHEMBL4047066 | 0.75 | — | — | |
| Meglumine SCHEMBL23363691 | 0.74 | KDM4E (1.00) | — | |
| Meglumine SCHEMBL22562873 | 0.74 | KDM4E (1.00) | — | |
| Meglumine SCHEMBL23363692 | 0.74 | KDM4E (1.00) | — | |
| Meglumine SCHEMBL724392 | 0.74 | KDM4E (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888658-A1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | Effector Therapeutics Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2017091585-A1 | EIF4-A-INHIBITING COMPOUNDS AND METHODS RELATED THERETO | EFFECTOR THERAPEUTICS, INC. (US) | 2017-06-01 | — | — | WO | disclosed |