SCHEMBL1891193

SCHEMBL1891193

OCCOC12C(F)(F)C3(OCCO)C(F)(F)C(OCCO)(C1(F)F)C(F)(F)C(OCCO)(C2(F)F)C3(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1890504 0.92 TSHR (0.30) TSHRMAPK1
SCHEMBL1888253 0.88 ALDH1A1 (0.30) TSHR
SCHEMBL820971 0.87 TSHR (0.30) TSHRMAPK1
SCHEMBL1883508 0.82
SCHEMBL1887049 0.81
SCHEMBL1237212 0.56
Di(Hydroxyethyl)Ether SCHEMBL1462 0.54
Di(Hydroxyethyl)Ether SCHEMBL2410410 0.54 TSHR (1.00) TSHRMAPK1MEN1KMT2A
SCHEMBL543753 0.54
Ethylene Glycol SCHEMBL25182687 0.51 TSHR (0.50) TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130320326-A1 INSULATING MATERIAL FORMING COMPOSITION FOR ELECTRONIC DEVICES, INSULATING MATERIAL FOR ELECTRONIC DEVICES, ELECTRONIC DEVICES AND THIN FILM TRANSISTOR IDEMITSU KOSAN CO., LTD. 2013-12-05 US disclosed
US-7939682-B2 Fluorine-containing adamantane derivative, fluorine-containing adamantane derivative having polymerizable group, and resin composition containing same IDEMITSU KOSAN CO., LTD. (JP) 2011-05-10 US disclosed
US-20090149665-A1 FLUORINE-CONTAINING ADAMANTANE DERIVATIVE, FLUORINE-CONTAINING ADAMANTANE DERIVATIVE HAVING POLYMERIZABLE GROUP, AND RESIN COMPOSITION CONTAINING SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-06-11 US disclosed
EP-1950190-A1 FLUORINE-CONTAINING ADAMANTANE DERIVATIVE, FLUORINE-CONTAINING ADAMANTANE DERIVATIVE HAVING POLYMERIZABLE GROUP, AND RESIN COMPOSITION CONTAINING SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149665-A1 FLUORINE-CONTAINING ADAMANTANE DERIVATIVE, FLUORINE-CONTAINING ADAMANTANE DERIVATIVE HAVING POLYMERIZABLE GROUP, AND RESIN COMPOSITION CONTAINING SAME TAS1R1, ADORA1, TAS2R1 TSHR 1786/4885MAPK1 2489/4885MEN1 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.