SCHEMBL18912653

SCHEMBL18912653

CCOCC(=O)NC(C)(C)CCOC(C)(C)CCn1cc(CNC(=O)C2CCC(CN3C(=O)CCC3=O)CC2)nn1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.36
▸ IL2 P60568 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23005883 0.88 TTR (0.33) TTRIL2
SCHEMBL25559713 0.81 TTR (0.34) TTRIL2
SCHEMBL23278432 0.81 TTR (0.43) TTRIL2
SCHEMBL27053407 0.80 TTR (0.39) TTRIL2
SCHEMBL25795469 0.77 CCKBR (0.35) —
SCHEMBL21132205 0.76 TTR (0.43) TTRIL2
SCHEMBL22388613 0.75 KLKB1 (0.37) TTRIL2
SCHEMBL25671065 0.75 TTR (0.44) TTRIL2
SCHEMBL25100593 0.74 TTR (0.42) TTRIL2
SCHEMBL17011377 0.74 TTR (0.56) TTRIL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170151356-A1 Camptothecin Conjugates of Anti-CD22 Antibodies for Treatment of B Cell Diseases IMMUNOMEDICS, INC. 2017-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170151356-A1 Camptothecin Conjugates of Anti-CD22 Antibodies for Treatment of B Cell Diseases CD22, CD2, CD2BP2 TTR 3467/4885IL2 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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