Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223599 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL4156930 | 0.83 | PDGFRB (0.64) | KDM4EALDH1A1POLBGAAPDGFRB | |
| SCHEMBL16161575 | 0.80 | PIK3CA (0.48) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL16161586 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL30223495 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL12199223 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL6701353 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1POLBGAANPC1 | |
| SCHEMBL782456 | 0.77 | PTGDR (0.47) | KDM4EALDH1A1POLBGAAPDGFRB | |
| Hydrochloric Acid SCHEMBL16161540 | 0.76 | PTGDR (0.46) | KDM4EALDH1A1POLBGAAPDGFRB | |
| SCHEMBL16161765 | 0.76 | PIK3CA (0.46) | KDM4EALDH1A1POLBGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152225-A9 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | UNIVERSITY OF EAST ANGLIA (GB) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152225-A9 | METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE | ITPA, PPA1, PPIP5K2 | KDM4E 2572/4885ALDH1A1 2656/4885POLB 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.