Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FABP1 | P07148 | 1/20 | 0.53 |
| ▸ | FABP6 | P51161 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14129594 | 0.87 | KDM4E (0.54) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL4640092 | 0.85 | NPC1 (0.64) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL18171881 | 0.83 | PDGFRB (0.61) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL780564 | 0.83 | PDGFRB (0.61) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL30223599 | 0.83 | KDM4E (0.66) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL18912907 | 0.83 | KDM4E (0.66) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL14098736 | 0.82 | MRGPRX4 (0.54) | PDGFRBPDGFRAKDM4EALDH1A1POLB | |
| SCHEMBL3908370 | 0.79 | PDGFRB (1.00) | PDGFRBPDGFRAKDM4EALDH1A1GAA | |
| SCHEMBL3910327 | 0.78 | PDGFRB (0.78) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL29558717 | 0.77 | ALDH1A1 (0.56) | PDGFRBPDGFRAKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115747838-A | Method for synthesizing amino-substituted quinoxalinone compound through electrochemical reaction | 南京师范大学 | 2023-03-07 | — | — | CN | disclosed |
| US-20090186918-A1 | Triazole Compounds as Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2009-07-23 | — | — | US | disclosed |
| CN-101300236-A | Triazole compounds as lipoxygenase inhibitors | BIOLIPOX AB (SE) | 2008-11-05 | — | — | CN | disclosed |
| EP-1943234-A1 | TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS | Biolipox AB (SE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007051982-A1 | TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS | BIOLIPOX AB (SE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186918-A1 | Triazole Compounds as Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | PDGFRB 2362/4885PDGFRA 2938/4885KDM4E 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.