Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CASP5 | P51878 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP9 | P55211 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30455214 | 0.83 | FDFT1 (0.42) | RENFDFT1PRCP | |
| SCHEMBL22266601 | 0.81 | PTPN1 (0.35) | RENPTPN1FDFT1 | |
| SCHEMBL17450537 | 0.79 | PRCP (0.43) | FDFT1PRCP | |
| SCHEMBL30272508 | 0.78 | REN (0.43) | RENPTPN1CMA1FDFT1PRCP | |
| SCHEMBL30455194 | 0.77 | FDFT1 (0.45) | RENFDFT1PRCP | |
| SCHEMBL30272489 | 0.76 | PRCP (0.46) | CASP3PRCP | |
| SCHEMBL22266614 | 0.76 | MDM4 (0.46) | CASP3 | |
| SCHEMBL30538838 | 0.76 | MDM4 (0.46) | CASP3 | |
| SCHEMBL22266611 | 0.76 | MDM4 (0.46) | CASP3 | |
| SCHEMBL30962356 | 0.75 | PRCP (0.46) | FDFT1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017089607-A1 | DERIVATIVES OF GAMMA-AMANITIN | HEIDELBERG PHARMA GMBH (DE) | 2017-06-01 | — | — | WO | disclosed |