Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18913913 | 0.87 | MAPT (0.43) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL18913912 | 0.87 | MAPT (0.46) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL18913818 | 0.86 | MAPT (0.44) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL1982952 | 0.81 | MAPT (0.47) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL1987813 | 0.81 | MEN1 (0.46) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL1984022 | 0.81 | POLB (0.62) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL6123191 | 0.81 | POLB (0.62) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL1982068 | 0.81 | POLB (0.62) | MAPTALDH1A1HTTSMN1; SMN2SIRT6 | |
| SCHEMBL1984298 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL1982735 | 0.81 | AKR1C3 (0.56) | MAPTALDH1A1SMN1; SMN2SIRT6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017088730-A1 | SILICONE-CONTAINING COMPOUND FOR RESISTING HEPATITIS C VIRUS INFECTION | 正大天晴药业集团股份有限公司 | 2017-06-01 | — | — | WO | disclosed |