Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18913915 | 1.00 | KDM4E (0.33) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL18913953 | 0.85 | MAPT (0.36) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL18913912 | 0.80 | MAPT (0.46) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL18913916 | 0.80 | KDM4E (0.36) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL18913819 | 0.79 | MAPT (0.38) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1989751 | 0.79 | MAPT (0.43) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1989823 | 0.79 | MAPT (0.43) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL14856415 | 0.79 | MAPT (0.43) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1982165 | 0.76 | KIF11 (0.47) | PRKCZ | |
| SCHEMBL1983143 | 0.76 | KIF11 (0.47) | PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017088730-A1 | SILICONE-CONTAINING COMPOUND FOR RESISTING HEPATITIS C VIRUS INFECTION | 正大天晴药业集团股份有限公司 | 2017-06-01 | — | — | WO | disclosed |