Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989823 | 1.00 | MAPT (0.43) | MAPTALDH1A1NPC1HPGDMAPK1 | |
| SCHEMBL1989751 | 1.00 | MAPT (0.43) | MAPTALDH1A1NPC1HPGDMAPK1 | |
| SCHEMBL237269 | 0.84 | PRKCZ (0.45) | MAPTALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL240803 | 0.84 | PRKCZ (0.45) | MAPTALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL1989822 | 0.84 | RIPK1 (0.38) | MAPK1SLC6A2SLC6A4SLC6A3RIPK1 | |
| SCHEMBL1983143 | 0.84 | KIF11 (0.47) | CYP3A4PRKCZ | |
| SCHEMBL2374410 | 0.84 | RIPK1 (0.38) | MAPK1SLC6A2SLC6A4SLC6A3RIPK1 | |
| SCHEMBL1982165 | 0.84 | KIF11 (0.47) | CYP3A4PRKCZ | |
| SCHEMBL240802 | 0.84 | PRKCZ (0.45) | MAPTALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL1982140 | 0.84 | MAPT (0.35) | MAPTALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015171162-A1 | ANTI-VIRAL COMPOUND | ABBVIE INC. (US) | 2015-11-12 | — | — | WO | disclosed |
| EP-2368890-B1 | Hepatitis C virus inhibitors | ABBVIE BAHAMAS LTD (BS) | 2013-04-17 | — | — | EP | disclosed |