Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 12/20 | 0.51 |
| ▸ | MC4R | P32245 | 6/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914422 | 0.88 | MC1R (0.49) | MC1RMC4RTACR1USP30PDE4B | |
| SCHEMBL18914417 | 0.76 | PDE4B (0.59) | MC1RMC4RTACR1MC5RKCNH2 | |
| SCHEMBL13525795 | 0.76 | PDE4B (0.59) | MC1RMC4RTACR1MC5RKCNH2 | |
| SCHEMBL3968947 | 0.76 | MC4R (0.50) | MC1RMC4RTACR1MC5RKCNH2 | |
| SCHEMBL1267149 | 0.76 | MC4R (0.50) | MC1RMC4RTACR1MC5RKCNH2 | |
| SCHEMBL13493029 | 0.76 | MC4R (0.50) | MC1RMC4RTACR1MC5RKCNH2 | |
| SCHEMBL1920145 | 0.75 | TACR1 (0.46) | MC1RMC4RTACR1MC5RKCNH2 | |
| SCHEMBL23168835 | 0.73 | MC1R (0.71) | MC1RMC4R | |
| SCHEMBL18914419 | 0.73 | MC1R (0.71) | MC1RMC4R | |
| SCHEMBL18914539 | 0.73 | MC1R (0.48) | MC1RMC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017090743-A1 | NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2017-06-01 | — | — | WO | disclosed |