Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 11/20 | 0.48 |
| ▸ | MC4R | P32245 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18914492 | 0.90 | MC1R (0.47) | MC1RMC4RKCNH2PRCP | |
| SCHEMBL18914380 | 0.74 | MC1R (0.63) | MC1RMC4RKCNH2PRCP | |
| SCHEMBL18914381 | 0.74 | MC1R (0.63) | MC1RMC4RKCNH2PRCP | |
| SCHEMBL5675788 | 0.73 | MC4R (0.51) | MC1RMC4RKCNH2PRCP | |
| SCHEMBL18914537 | 0.73 | MC1R (0.51) | MC1RMC4RKCNH2 | |
| Hydrochloric Acid SCHEMBL1920434 | 0.71 | MC4R (0.51) | MC4RKCNH2 | |
| SCHEMBL1920424 | 0.71 | MC4R (0.54) | MC4RKCNH2PRCP | |
| SCHEMBL12533727 | 0.71 | MC4R (0.54) | MC4RKCNH2PRCP | |
| SCHEMBL29327388 | 0.71 | MC4R (0.54) | MC4RKCNH2PRCP | |
| SCHEMBL1921102 | 0.71 | MC4R (0.54) | MC4RKCNH2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017090743-A1 | NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2017-06-01 | — | — | WO | disclosed |