SCHEMBL189158

SCHEMBL189158

CC([C@H](N)C(=O)O)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.52
SLC1A3 P43003 3/20 0.39
SLC1A2 P43004 3/20 0.39
SLC1A1 P43005 2/20 0.39
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
PTGS1 P23219 1/20 0.36
TP53 P04637 1/20 0.35
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
ENPEP Q07075 2/20 0.31
GABRP O00591 3/20 0.31
GABRD O14764 3/20 0.31
GABRA1 P14867 3/20 0.31
GABRB1 P18505 3/20 0.31
GABRG2 P18507 3/20 0.31
GABRB3 P28472 3/20 0.31
GABRA5 P31644 3/20 0.31
GABRA3 P34903 3/20 0.31
GABRA2 P47869 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4420550 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL4419903 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL4423815 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL27915349 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL16753714 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL4426649 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL189157 1.00 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
Hydrochloric Acid SCHEMBL28009300 0.98 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
Hydrochloric Acid SCHEMBL15533962 0.98 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1
SCHEMBL7044455 0.81 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250130224-A1 PHOTOREACTIVE ANTIBODY BINDING DOMAINS WITH EPITOPE TAGS FOR MULTIPLEXED ANTIBODY LABELING, DETECTION, AND PURIFICATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-04-24 US claimed
EP-4380620-A2 PHOTOREACTIVE ANTIBODY BINDING DOMAINS WITH EPITOPE TAGS FOR MULTIPLEXED ANTIBODY LABELING, DETECTION, AND PURIFICATION The Trustees of The University of Pennsylvania (US) 2024-06-12 EP claimed
CN-116675951-A Fluorine-containing epoxy resin for high-performance carbon fiber prepreg and preparation method thereof 山东万亿体育健康服务有限公司 2023-09-01 CN claimed
CN-116365044-A Electrolyte, secondary battery and electric equipment 欣旺达电动汽车电池有限公司 2023-06-30 CN claimed
WO-2023014778-A2 PHOTOREACTIVE ANTIBODY BINDING DOMAINS WITH EPITOPE TAGS FOR MULTIPLEXED ANTIBODY LABELING, DETECTION, AND PURIFICATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-02-09 WO claimed
US-20130012690-A1 METHOD FOR STABILIZATION OF PROTEINS USING NON-NATURAL AMINO ACIDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-01-10 US claimed
US-20090326196-A1 Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same TRUSTEES OF TUFTS COLLEGE 2009-12-31 US claimed
US-20090221790-A1 METHOD FOR STABILIZATION OF PROTEINS USING NON-NATURAL AMINO ACIDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2009-09-03 US claimed
EP-1993582-A2 PROTEINS CONTAINING A FLUORINATED AMINO ACID, AND METHODS OF USING SAME Trustees Of Tufts College (US) 2008-11-26 EP claimed
WO-2007084527-A2 PROTEINS CONTAINING A FLUORINATED AMINO ACID, AND METHODS OF USING SAME TRUSTEES OF TUFTS COLLEGE (US) 2007-07-26 WO claimed
US-20040214988-A1 Method for stabilization of proteins using non-natural amino acids CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-10-28 US claimed
JP-61254544-A None JP disclosed
EP-4687443-A1 METHOD FOR FUNCTIONALISING A SOLID SUBSTRATE WITH A PEPTIDE CONJUGATE Genepep (FR) 2026-02-11 EP disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US disclosed
WO-2001027140-A1 CASPASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF CHEMOTHERAPY AND RADIATION THERAPY INDUCED CELL DEATH CYTOVIA, INC. (US) 2001-04-19 WO disclosed
EP-1076563-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF Cytovia, Inc. (US) 2001-02-21 EP disclosed
US-6153591-A PROTECTING NERVOUS SYSTEM FOLLOWING FOCAL ISCHEMIA AND GLOBAL ISCHEMIA; ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, PRION DISEASES, PARKINSON'S DISEASE, MULTIPLE SCLEROSIS, AMYOTROPHIC LATERAL SCLEROSIS, ALOPACIA, RHEUMATOID ARTHRITIS CYTOVIA, INC. (US) 2000-11-28 US disclosed
WO-1999047154-A1 DIPEPTIDE CASPASE INHIBITORS AND THE USE THEREOF CYTOVIA, INC. (US) 1999-09-23 WO disclosed
JP-S61254544-A PRODUCTION OF 4,4,4-TRIFLUOROVALINE COMPOUND ASAHI GLASS CO LTD 1986-11-12 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 SLC7A5 1405/4885SLC1A3 1024/4885SLC1A2 1557/4885
US-20090326196-A1 Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same DNPEP, NPEPPS, ANPEP SLC7A5 618/4885SLC1A3 385/4885SLC1A2 647/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B SLC7A5 1050/4885SLC1A3 595/4885SLC1A2 708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.