Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 3/20 | 0.31 |
| ▸ | GABRD | O14764 | 3/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420550 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL4423815 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL27915349 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL16753714 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL189158 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL4426649 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL189157 | 1.00 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28009300 | 0.98 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15533962 | 0.98 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL7044455 | 0.81 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309198-B2 | N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20150152050-A1 | N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-06-04 | — | — | US | disclosed |
| CN-104470895-A | N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase | Bayer Pharma AG | 2015-03-25 | — | — | CN | disclosed |
| US-20090326196-A1 | Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same | TRUSTEES OF TUFTS COLLEGE | 2009-12-31 | — | — | US | disclosed |
| US-20090326196-A1 | Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same | TRUSTEES OF TUFTS COLLEGE | 2009-12-31 | — | — | US | disclosed |
| US-20090326196-A1 | Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same | TRUSTEES OF TUFTS COLLEGE | 2009-12-31 | — | — | US | disclosed |
| US-7371867-B2 | Non-racemic trifluoroleucine, and methods of making and using | TRUSTEES OF TUFTS COLLEGE (US) | 2008-05-13 | — | — | US | disclosed |
| US-7371867-B2 | Non-racemic trifluoroleucine, and methods of making and using | TRUSTEES OF TUFTS COLLEGE (US) | 2008-05-13 | — | — | US | disclosed |
| US-7371867-B2 | Non-racemic trifluoroleucine, and methods of making and using | TRUSTEES OF TUFTS COLLEGE (US) | 2008-05-13 | — | — | US | disclosed |
| WO-2007084527-A2 | PROTEINS CONTAINING A FLUORINATED AMINO ACID, AND METHODS OF USING SAME | TRUSTEES OF TUFTS COLLEGE (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070112200-A1 | Non-racemic hexafluoreleucine,and methods of making and using it | TRUSTEES OF TUFTS COLLEGE (US) | 2007-05-17 | — | — | US | disclosed |
| US-20070112200-A1 | Non-racemic hexafluoreleucine,and methods of making and using it | TRUSTEES OF TUFTS COLLEGE (US) | 2007-05-17 | — | — | US | disclosed |
| US-20070112200-A1 | Non-racemic hexafluoreleucine,and methods of making and using it | TRUSTEES OF TUFTS COLLEGE (US) | 2007-05-17 | — | — | US | disclosed |
| US-7132559-B2 | Non-racemic hexafluoroleucine, and methods of making and using it | TRUSTEES OF TUFTS COLLEGE (US) | 2006-11-07 | — | — | US | disclosed |
| US-20040138493-A1 | Non-racemic hexafluoreleucine, and methods of making and using it | TRUSTEES OF TUFTS COLLEGE | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152050-A1 | N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | GUCY1A2, GUCY1A1, GUCY1B2 | SLC7A5 4075/4885SLC1A3 2623/4885SLC1A2 2677/4885 |
| US-20090326196-A1 | Proteins Containing a Fluorinated Amino Acid, and Methods of Using Same | DNPEP, NPEPPS, ANPEP | SLC7A5 618/4885SLC1A3 385/4885SLC1A2 647/4885 |
| US-20070112200-A1 | Non-racemic hexafluoreleucine,and methods of making and using it | CRYZ, FABP5, FAU | SLC7A5 1167/4885SLC1A3 2513/4885SLC1A2 2705/4885 |
| US-20040138493-A1 | Non-racemic hexafluoreleucine, and methods of making and using it | NPFFR1, FNTB, CRYZ | SLC7A5 1102/4885SLC1A3 2419/4885SLC1A2 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.