Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 14/20 | 0.59 |
| ▸ | PDE6C | P51160 | 8/20 | 0.59 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407726 | 1.00 | PDE5A (0.59) | PDE5APDE6CPDE11A | |
| SCHEMBL6634306 | 0.86 | PDE5A (0.56) | PDE5APDE6CPDE11A | |
| SCHEMBL1887267 | 0.86 | PDE5A (0.56) | PDE5APDE6CPDE11A | |
| SCHEMBL6407766 | 0.75 | PDE5A (0.42) | PDE5APDE6C | |
| SCHEMBL6407728 | 0.74 | PDE5A (0.83) | PDE5A | |
| SCHEMBL1891581 | 0.74 | PDE5A (0.83) | PDE5A | |
| SCHEMBL6407209 | 0.73 | PDE5A (0.61) | PDE5APDE6CPDE11A | |
| SCHEMBL6777087 | 0.70 | PDE5A (0.57) | PDE5APDE6CPDE11A | |
| SCHEMBL6777089 | 0.70 | PDE5A (0.57) | PDE5APDE6CPDE11A | |
| SCHEMBL6775612 | 0.70 | PDE5A (0.57) | PDE5APDE6CPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150086504-A1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2015-03-26 | — | — | US | disclosed |
| US-20110112115-A1 | POLYMERIC MICROEMULSIONS | ARIEN ALBERTINA MARIA EDUARDA | 2011-05-12 | — | — | US | disclosed |
| EP-1504047-B1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2007-12-12 | — | — | EP | disclosed |
| US-20060034797-A1 | Polymeric micromulsions | ETHICON INC. | 2006-02-16 | — | — | US | disclosed |
| EP-1504047-A1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003093344-A1 | POLYMERIC MICROEMULSIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-13 | — | — | WO | disclosed |