Azetidine

Azetidine

SCHEMBL18917062

C1CNC1.CCOC(=O)C1CCCN1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.43
DPP7 Q9UHL4 2/20 0.38
SCN4A P35499 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
DPP4 P27487 1/20 0.37
FAP Q12884 1/20 0.37
DPP8 Q6V1X1 1/20 0.37
DPP9 Q86TI2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NOS2 P35228 2/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133135 0.96 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A4
SCHEMBL115996 0.96 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A4
SCHEMBL3330660 0.96 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A4
SCHEMBL10829027 0.96 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A4
Hydrochloric Acid SCHEMBL1073479 0.95 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A4
Ammonia Solution, Strong SCHEMBL6516951 0.95 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A4
Hydrochloric Acid SCHEMBL3530351 0.95 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A4
Hydrochloric Acid SCHEMBL133134 0.95 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A4
SCHEMBL135813 0.91 SLC6A2 (0.44) PRCPSLC6A2SLC6A4SLC6A3MAPT
SCHEMBL1929065 0.91 SLC6A2 (0.44) PRCPSLC6A2SLC6A4SLC6A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2888252-B1 BENZOFURAZAN ANTI-AMYLOID COMPOUNDS AND METHODS TREVENTIS CORP (US) 2017-06-07 EP disclosed