Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6516951

CCOC(=O)[C@H]1CCCN1.N

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.44
DPP7 Q9UHL4 2/20 0.39
SCN4A P35499 1/20 0.39
SLC6A2 P23975 3/20 0.38
SLC6A3 Q01959 3/20 0.38
SLC6A4 P31645 2/20 0.38
NOS2 P35228 2/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
DPP4 P27487 1/20 0.38
FAP Q12884 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PPM1B O75688 1/20 0.38
PTPN1 P18031 1/20 0.38
PPP1CC P36873 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10829027 0.98 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A3
SCHEMBL133135 0.98 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A3
SCHEMBL115996 0.98 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A3
SCHEMBL3330660 0.98 PRCP (0.45) PRCPDPP7SCN4ASLC6A2SLC6A3
Hydrochloric Acid SCHEMBL1073479 0.96 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A3
Hydrochloric Acid SCHEMBL3530351 0.96 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A3
Hydrochloric Acid SCHEMBL133134 0.96 PRCP (0.44) PRCPDPP7SCN4ASLC6A2SLC6A3
Azetidine SCHEMBL18917062 0.95 PRCP (0.43) PRCPDPP7SCN4ASLC6A2SLC6A3
SCHEMBL135813 0.93 SLC6A2 (0.44) PRCPSLC6A2SLC6A3SLC6A4ALDH1A1
SCHEMBL1929065 0.93 SLC6A2 (0.44) PRCPSLC6A2SLC6A3SLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483408-A4 NANOSTRUCTURES CONTAINING PNA JOINING OR FUNCTIONAL ELEMENTS NANOFRAMES INC (US) 2005-06-22 EP disclosed
EP-1483408-A1 NANOSTRUCTURES CONTAINING PNA JOINING OR FUNCTIONAL ELEMENTS Nanoframes, Inc. (US) 2004-12-08 EP disclosed
US-6716961-B2 Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2004-04-06 US disclosed
US-20030215903-A1 Nanostructures containing PNA joining or functional elements NANOFRAMES INC. 2003-11-20 US disclosed
US-20030198956-A1 Staged assembly of nanostructures NANOFRAMES, INC. 2003-10-23 US disclosed
WO-2003072829-A1 NANOSTRUCTURES CONTAINING PNA JOINING OR FUNCTIONAL ELEMENTS NANOFRAMES, INC. (US) 2003-09-04 WO disclosed
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone POLL, HNRNPL, RNGTT PRCP 598/4885DPP7 1416/4885SCN4A 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.