Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253092 | 0.75 | KDM4E (0.44) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL29454008 | 0.65 | MEN1 (1.00) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL881196 | 0.65 | MEN1 (1.00) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL11088343 | 0.65 | MAOA (0.41) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL12201063 | 0.65 | — | — | |
| SCHEMBL11293127 | 0.61 | MAOA (0.38) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL3620608 | 0.60 | MAOA (0.37) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL11508916 | 0.57 | CDC25B (0.35) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL11510069 | 0.57 | CDC25B (0.35) | KDM4EMEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL5808584 | 0.56 | MAPT (0.56) | KDM4EMEN1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228362-B1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | DOW CORNING TORAY CO LTD (JP) | 2017-06-07 | — | — | EP | disclosed |