SCHEMBL18917591

SCHEMBL18917591

CO[Si](OC)(OC)OC(O[Si](OC)(OC)OC)[SiH2]CCCOCC1CO1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150316 0.87 TSHR (0.52) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL517984 0.83 TSHR (0.55) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL3951784 0.83 SMN1; SMN2 (0.50) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL22492790 0.83 TSHR (0.47) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL22492798 0.83 TSHR (0.47) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL22492766 0.83 SMN1; SMN2 (0.50) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL22492688 0.82 TSHR (0.46) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL465573 0.78 SMN1; SMN2 (0.54) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL464858 0.78 TSHR (0.52) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1
SCHEMBL27630770 0.77 TSHR (0.50) ALDH1A1TDP1TSHRSMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10053526-B2 Catalyst for conjugated diene polymerization, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and compositions comprising foregoing UBE INDUSTRIES, LTD. (JP) 2018-08-21 US disclosed
US-20170158786-A1 CATALYST FOR CONJUGATED DIENE POLYMERIZATION, CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, POLYBUTADIENE, AND COMPOSITIONS COMPRISING FOREGOING UBE INDUSTRIES, LTD. (JP) 2017-06-08 US disclosed