Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492798 | 0.89 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL150316 | 0.87 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL3951784 | 0.83 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL18917591 | 0.83 | ALDH1A1 (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL22492766 | 0.83 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL22492688 | 0.82 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL517984 | 0.80 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL465573 | 0.78 | SMN1; SMN2 (0.54) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL22492792 | 0.76 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL3745028 | 0.75 | SMN1; SMN2 (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3719025-A1 | SILOXANE COMPOUND AND METHOD FOR PRODUCING SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |