SCHEMBL464858

SCHEMBL464858

CO[Si](OC)(OC)O[SiH2]CCCOCC1CO1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721126 0.86 SMN1; SMN2 (0.53) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8002488 0.85 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5522882 0.82 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL150450 0.82 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL332064 0.79 ALDH1A1 (0.41) ALDH1A1
SCHEMBL7215607 0.79 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL17727830 0.78 TSHR (0.65) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL18917591 0.78 ALDH1A1 (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL753215 0.78 TSHR (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1412958 0.78 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002837-B1 Room-temperature curable silicone rubber composition DOW CORNING TORAY SILICONE (JP) 2003-06-11 EP claimed
US-4191573-A O-QUINONE DIAZIDE, AN ALKALI-SOLUBLE ARYL AZIDE, A POLYAMIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-03-04 US claimed
EP-2440647-B1 MICROCAPSULES CONTAINING MICROORGANISMS DEVAN CHEMICALS NV (BE) 2022-10-12 EP disclosed
US-10479963-B2 Microcapsules containing microorganisms DEVAN CHEMICALS NV (BE) 2019-11-19 US disclosed
EP-2440647-A1 MICROCAPSULES CONTAINING MICROORGANISMS Devan Chemicals Nv (BE) 2012-04-18 EP disclosed
US-20120076864-A1 Microcapsules Containing Microorganisms DEVAN CHEMICALS NV (BE) 2012-03-29 US disclosed
EP-1599559-B1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-30 EP disclosed
WO-2010142401-A1 MICROCAPSULES CONTAINING MICROORGANISMS DEVAN CHEMICALS NV (BE) 2010-12-16 WO disclosed
US-7642715-B2 Light-emitting device comprising an improved gas barrier layer, method for manufacturing light-emitting device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2010-01-05 US disclosed
US-7157399-B2 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES INC. (US) 2007-01-02 US disclosed
US-20060158111-A1 Light-emitting device, method for manufacturing light-emitting device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2006-07-20 US disclosed
EP-1599559-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-11-30 EP disclosed
US-6949603-B2 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-27 US disclosed
US-20040242812-A1 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES INC. 2004-12-02 US disclosed
US-6825298-B2 CATALYTIC FREE RADICAL ADDITION POLYMERIZATION OF OLEFINICALLY UNSATURATED MONOMOERS; CURING ADHESIVES; BONDING STRENGTH, HEAT RESISTANCE DOW GLOBAL TECHNOLOGIES INC. 2004-11-30 US disclosed
US-20040220363-A1 Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components DOW GLOBAL TECHNOLOGIES LLC 2004-11-04 US disclosed
US-20040210015-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS SONNENSCHEIN MARK F (US) 2004-10-21 US disclosed
WO-2004078871-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-09-16 WO disclosed
US-6777512-B1 MONOMERS, OLIGOMERS OR POLYMERS HAVING A SILOXANE BACKBONE CONTAINS ACRYLATE FUNCTIONAL MOIETIES DOW GLOBAL TECHNOLOGIES INC. 2004-08-17 US disclosed