Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenylphosphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.94 |
| ▸ | CA4 | P22748 | 1/20 | 0.94 |
| ▸ | CA5A | P35218 | 1/20 | 0.94 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
| ▸ | PGK2 | P07205 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylphosphonic Acid SCHEMBL269853 | 0.97 | CA2 (1.00) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL28151870 | 0.97 | CA2 (1.00) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL34998 | 0.97 | CA2 (1.00) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL7951127 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL11422650 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL16413784 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL588197 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL911646 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL17626563 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 | |
| Phenylphosphonic Acid SCHEMBL11847565 | 0.94 | CA2 (0.94) | CA2CA4CA5ACFTRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428280-B2 | Method for manufacturing of multi-level pore zeolite and utilization as catalyst for hydroisomerization of normal paraffins of multi-level pore zeolite prepared thereby | S-OIL CORPORATION (KR) | 2019-10-01 | — | — | US | disclosed |
| US-20170158970-A1 | METHOD FOR MANUFACTURING OF MULTI-LEVEL PORE ZEOLITE AND UTILIZATION AS CATALYST FOR HYDROISOMERIZATION OF NORMAL PARAFFINS OF MULTI-LEVEL PORE ZEOLITE PREPARED THEREBY | S-OIL CORPORATION (KR) | 2017-06-08 | — | — | US | disclosed |