Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | TST | Q16762 | 1/20 | 0.59 |
| ▸ | VDR | P11473 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892018 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1887971 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1896654 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1896655 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1897124 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1887969 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1897125 | 1.00 | ALDH1A1 (0.59) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1897965 | 0.88 | VDR (0.53) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL12980541 | 0.88 | VDR (0.53) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL12981279 | 0.88 | VDR (0.53) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200201-A1 | Enzymatic Production or Chemical Synthesis and Uses for 5,7-Dienes and UVB Conversion Products Thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2014-07-17 | — | — | US | disclosed |
| US-20120258938-A1 | Enzymatic Production or Chemical Synthesis and Uses for 5,7-Dienes and UVB Conversion Products Thereof | SLOMINSKI ANDREJ (US) | 2012-10-11 | — | — | US | disclosed |
| US-20110118228-A1 | Enzymatic production or chemical synthesis and uses for 5,7-dienes and UVB conversion products thereof | SLOMINSKI ANDRZEJ | 2011-05-19 | — | — | US | disclosed |