Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.73 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | TPH1 | P17752 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18920610 | 0.98 | ANPEP (0.71) | ANPEPENPEPALDH1A1TP53TSHR | |
| Hydrochloric Acid SCHEMBL21144830 | 0.98 | ANPEP (0.71) | ANPEPENPEPALDH1A1TP53TSHR | |
| SCHEMBL8099973 | 0.85 | ANPEP (0.69) | ANPEPENPEPALDH1A1TP53TSHR | |
| SCHEMBL18930227 | 0.84 | ANPEP (0.53) | ANPEPENPEPALDH1A1TSHREPHX1 | |
| SCHEMBL29098741 | 0.83 | ANPEP (0.67) | ANPEPENPEPALDH1A1TP53TSHR | |
| Hydrochloric Acid SCHEMBL21144942 | 0.82 | ANPEP (0.51) | ANPEPENPEPALDH1A1TSHRTPH1 | |
| Hydrochloric Acid SCHEMBL21144940 | 0.82 | ANPEP (0.51) | ANPEPENPEPALDH1A1TSHRTPH1 | |
| SCHEMBL18307031 | 0.82 | KMT2A (0.55) | ANPEPENPEPALDH1A1TPH1SLC7A5 | |
| SCHEMBL27077444 | 0.82 | ANPEP (0.65) | ANPEPENPEPALDH1A1TP53TSHR | |
| SCHEMBL6188688 | 0.80 | ANPEP (0.74) | ANPEPENPEPFOLH1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654818-B2 | Furane derivatives as inhibitors of ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-05-19 | — | — | US | disclosed |
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |
| US-20190218196-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-07-18 | — | — | US | disclosed |
| EP-3383865-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017093272-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-08 | — | — | WO | disclosed |
| WO-2017093272-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218196-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | ATAD2, ATAD2B, TAF1L | ANPEP 3136/4885ENPEP 4174/4885ALDH1A1 1538/4885 |
| US-10654818-B2 | Furane derivatives as inhibitors of ATAD2 | ATAD2, ATAD2B, TAF1L | ANPEP 3136/4885ENPEP 4174/4885ALDH1A1 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.