ATAD2B — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL16008814	0.64	2/20
Gsk620 (SCHEMBL18584671)	1.00	1/20
SCHEMBL18617026	0.92	1/20
SCHEMBL18584911	0.92	1/20
SCHEMBL18616175	0.90	1/20
SCHEMBL18616212	0.85	1/20
SCHEMBL18617320	0.84	1/20
SCHEMBL18584916	0.83	1/20
SCHEMBL18585065	0.82	1/20
SCHEMBL18616076	0.82	1/20
SCHEMBL18616313	0.82	1/20
SCHEMBL18617886	0.82	1/20
SCHEMBL18689861	0.82	1/20
SCHEMBL18617291	0.82	1/20
SCHEMBL18616092	0.82	1/20
SCHEMBL18584584	0.82	1/20
SCHEMBL18616924	0.81	1/20
SCHEMBL18616984	0.81	1/20
SCHEMBL18617054	0.81	1/20
SCHEMBL18617150	0.81	1/20

Clinical trials — most relevant to ATAD2B by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients	PHASE3	UNKNOWN
A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation	PHASE2/PHASE3	RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)	PHASE1/PHASE2	RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma	PHASE1/PHASE2	COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load	PHASE1	COMPLETED
Genetic Basis of Abdominal Aortic Aneurysm	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Pathogenetic Basis of Aortopathy and Aortic Valve Disease	nan	ACTIVE_NOT_RECRUITING
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm	nan	COMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Amyotrophic Lateral Sclerosis (ALS) Families Project	nan	RECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk	nan	NOT_YET_RECRUITING
Familial Intracranial Aneurysm Study II	nan	COMPLETED
Genetic of Intellectual Deficiency and Autism Spectrum Disorders (RaDiCo-GenIDA)	nan	RECRUITING
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias	nan	COMPLETED
Epigenomic Profiling of Circulating Cell-Free DNA (cfDNA) to Characterize the Dynamic Evolution of Molecular Subtypes in Extensive-Stage Small Cell Lung Cancer During First-Line Chemoimmunotherapy	nan	NOT_YET_RECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics	nan	UNKNOWN
Mayo AVC Registry and Biobank	nan	RECRUITING
Genetics and Psychopathology in the 22q11 Deletion Syndrome	nan	UNKNOWN
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Genetics of Familial and Sporadic ALS	nan	COMPLETED
Gene Analysis of Parkinson's Disease	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ATAD2B binder may also engage these)

Protein	Name	Similarity
P54816	—	1.000	P54816 →
ATAD2	ATPase family AAA domain-containing protein 2	1.000	landscape →
Q05AS3	—	0.998	Q05AS3 →
F4JZ68	—	0.998	F4JZ68 →
Q9AWM8	—	0.998	Q9AWM8 →
P40340	—	0.998	P40340 →
Q5SVQ0	—	0.998	Q5SVQ0 →
A4IHT0	—	0.997	A4IHT0 →
KAT6B	Histone acetyltransferase KAT6B	0.997	landscape →
Q8BMD7	—	0.997	Q8BMD7 →
Q5HZJ0	—	0.996	Q5HZJ0 →
BRPF3	Bromodomain and PHD finger-containing protein 3	0.996	landscape →
Q6GX84	—	0.996	Q6GX84 →
G5EFI8	—	0.996	G5EFI8 →
Q96P47	—	0.996	Q96P47 →
B7PXE3	—	0.996	B7PXE3 →
Q6IVY4	—	0.996	Q6IVY4 →
Q60QD1	—	0.996	Q60QD1 →
Q6AZT2	—	0.996	Q6AZT2 →
Q9HDY4	—	0.996	Q9HDY4 →
Q700C2	—	0.996	Q700C2 →
A7MBB4	—	0.996	A7MBB4 →
Q9LSP8	—	0.995	Q9LSP8 →
Q9C6G0	—	0.995	Q9C6G0 →
Q4R8E0	—	0.995	Q4R8E0 →
Q9XX14	—	0.995	Q9XX14 →
A7T395	—	0.995	A7T395 →
Q19192	—	0.995	Q19192 →
Q9H329	—	0.995	Q9H329 →
A8XU52	—	0.995	A8XU52 →