⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197403 | 0.81 | — | — | |
| SCHEMBL13692972 | 0.80 | — | — | |
| SCHEMBL292359 | 0.80 | — | — | |
| SCHEMBL17128629 | 0.78 | ADH1B (0.59) | — | |
| SCHEMBL6491790 | 0.78 | — | — | |
| SCHEMBL1766882 | 0.78 | — | — | |
| SCHEMBL5967504 | 0.78 | ADH1B (0.59) | — | |
| SCHEMBL7808900 | 0.78 | — | — | |
| SCHEMBL14049815 | 0.78 | ADH1B (0.59) | — | |
| SCHEMBL6023974 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118476-A1 | Process for Preparing Chiral Compounds | PFIZER INC. | 2011-05-19 | — | — | US | claimed |
| EP-2185713-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | Pfizer Products Inc. (US) | 2010-05-19 | — | — | EP | claimed |
| WO-2009019561-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2009-02-12 | — | — | WO | claimed |
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | claimed |
| US-20160220707-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | AVELAS ACQUISITION CORPORATION | 2016-08-04 | — | — | US | disclosed |
| US-9079877-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-9079877-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-9079877-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2015-07-14 | — | — | US | disclosed |
| EP-2185713-B1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2532660-B1 | Process for preparing chiral compounds | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2532660-B1 | Process for preparing chiral compounds | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2185713-B1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| CN-101084236-A | excitatory amino acid prodrugs | LILLY CO ELI (US) | 2007-12-05 | — | — | CN | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |