⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892069 | 0.78 | — | — | |
| SCHEMBL1766882 | 0.77 | — | — | |
| SCHEMBL3197403 | 0.73 | — | — | |
| SCHEMBL6491790 | 0.71 | — | — | |
| SCHEMBL7808900 | 0.71 | — | — | |
| SCHEMBL8068062 | 0.70 | ADH1B (0.71) | — | |
| SCHEMBL499577 | 0.69 | — | — | |
| SCHEMBL11322360 | 0.67 | ADH1B (0.72) | — | |
| SCHEMBL979732 | 0.67 | ADH1B (0.72) | — | |
| SCHEMBL8764004 | 0.67 | ADH1B (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105559-B2 | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2006-09-12 | — | — | US | claimed |
| US-20050239860-A1 | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2005-10-27 | — | — | US | claimed |
| EP-1482940-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-12-08 | — | — | EP | claimed |
| EP-1432687-A2 | SUBSTITUTED 5-MEMBERED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-06-30 | — | — | EP | claimed |
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-04-29 | — | — | US | claimed |
| WO-2003093242-A2 | SUBSTITUTED 5-MEMBERED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-11-13 | — | — | WO | claimed |
| US-20030162776-A1 | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2003-08-28 | — | — | US | claimed |
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | claimed |
| US-7105559-B2 | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-6969715-B2 | 6-membered heterocyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| US-20050239860-A1 | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2005-10-27 | — | — | US | disclosed |
| US-20050153965-A1 | Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2005-07-14 | — | — | US | disclosed |
| EP-1482940-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6828338-B2 | Protease inhibitor; anticoagulant | PHARMACIA CORPORATION | 2004-12-07 | — | — | US | disclosed |
| EP-1432687-A2 | SUBSTITUTED 5-MEMBERED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-06-30 | — | — | EP | disclosed |
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-04-29 | — | — | US | disclosed |
| WO-2003093242-A2 | SUBSTITUTED 5-MEMBERED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
| US-6624180-B2 | Such as 2-(2-(N-((4-aminoiminomethylphenyl)methyl)-3-(3-aminophenyl)-6-(N,N -dimethylhydrazino)-1-oxypyridinyl))acetami de which inhibit serine proteases for preventing and treating thrombotis | PHARMACIA CORPORATION | 2003-09-23 | — | — | US | disclosed |
| US-20030162776-A1 | Substituted 5-membered polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2003-08-28 | — | — | US | disclosed |
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |