Sugi Predict

Sugi Predict / Compounds / SCHEMBL2197644

SCHEMBL2197644

SCHEMBL2197644

c1ccc(CN[C@H]2CCCC[C@@H]2NCc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 7/20 0.58
▸ MAOA P21397 4/20 0.58
▸ GRIN2B Q13224 2/20 0.53
▸ FUCA1 P04066 1/20 0.50
▸ SSTR3 P32745 3/20 0.49
▸ BCHE P06276 2/20 0.49
▸ ACHE P22303 2/20 0.49
▸ BACE1 P56817 2/20 0.49
▸ MEN1 O00255 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ HRH3 Q9Y5N1 1/20 0.47
▸ MAOB P27338 3/20 0.46
▸ EPHX1 P07099 1/20 0.46
▸ HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2798417 1.00 KDM1A (0.58) KDM1AMAOAGRIN2BFUCA1SSTR3
SCHEMBL2936924 1.00 KDM1A (0.58) KDM1AMAOAGRIN2BFUCA1SSTR3
SCHEMBL2197651 1.00 KDM1A (0.58) KDM1AMAOAGRIN2BFUCA1SSTR3
SCHEMBL491107 1.00 KDM1A (0.58) KDM1AMAOAGRIN2BFUCA1SSTR3
SCHEMBL2198525 1.00 KDM1A (0.58) KDM1AMAOAGRIN2BFUCA1SSTR3
Bromide SCHEMBL17822680 0.98 KDM1A (0.56) KDM1AMAOAGRIN2BFUCA1SSTR3
Bromide SCHEMBL16799767 0.98 KDM1A (0.56) KDM1AMAOAGRIN2BFUCA1SSTR3
Bromide SCHEMBL18129441 0.98 KDM1A (0.56) KDM1AMAOAGRIN2BFUCA1SSTR3
Ammonia Solution, Strong SCHEMBL2987109 0.98 KDM1A (0.56) KDM1AMAOAGRIN2BFUCA1SSTR3
Bromide SCHEMBL17822672 0.98 KDM1A (0.56) KDM1AMAOAGRIN2BFUCA1SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285402-B Pregabalin of Process for the preparation of intermediates 常州大学 2025-05-09 — — CN disclosed
US-20250129079-A1 SALTS AND PROCESSES OF PREPARING A PI3K INHIBITOR INCYTE CORPORATION 2025-04-24 — — US disclosed
EP-4086240-B1 PYRROLIDINONE HERBICIDES FMC CORP (US) 2025-02-05 — — EP disclosed
US-12077503-B2 Substituted cyclic amides and their use as herbicides FMC CORPORATION (US) 2024-09-03 — — US disclosed
CN-117800973-A Salts of PI3K inhibitors and methods of making the same 因赛特控股公司 2024-04-02 — — CN disclosed
CN-117777139-A Salts of PI3K inhibitors and methods of making the same 因赛特控股公司 2024-03-29 — — CN disclosed
CN-117736209-A Salts of PI3K inhibitors and methods of making the same 因赛特控股公司 2024-03-22 — — CN disclosed
US-20240025853-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES FMC CORPORATION 2024-01-25 — — US disclosed
CN-117285402-A Preparation method of pregabalin intermediate 常州大学 2023-12-26 — — CN disclosed
US-11787765-B2 Substituted cyclic amides and their use as herbicides FMC CORPORATION (US) 2023-10-17 — — US disclosed
US-20220024934-A1 SALTS AND PROCESSES OF PREPARING A PI3K INHIBITOR INCYTE CORPORATION 2022-01-27 — — US disclosed
US-10961197-B2 Metal chelators for imaging, therapeutics, and bioanalysis THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2021-03-30 — — US disclosed
WO-2018092916-A1 NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE 宇部興産株式会社 2018-05-24 — — WO disclosed
WO-2018048879-A1 METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-03-15 — — WO disclosed
US-7977372-B2 Ortho aminoamides for the treatment of cancer HOFFMANN-LA ROCHE INC. (US) 2011-07-12 — — US disclosed
US-7977372-B2 Ortho aminoamides for the treatment of cancer HOFFMANN-LA ROCHE INC. (US) 2011-07-12 — — US disclosed
WO-2010094678-A1 NOVEL ORTHO-AMINOAMIDES FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2010-08-26 — — WO disclosed
US-20100216806-A1 ORTHO AMINOAMIDES FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE, INC. 2010-08-26 — — US disclosed
US-20100216806-A1 ORTHO AMINOAMIDES FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE, INC. 2010-08-26 — — US disclosed
WO-2008003809-A1 ANTITUMOUR COMPOUNDS PHARMA MAR, S.A. (ES) 2008-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787765-B2 Substituted cyclic amides and their use as herbicides NIT2, ARG1, CNPY2 KDM1A 796/4885MAOA 1121/4885GRIN2B 1289/4885
US-20100216806-A1 ORTHO AMINOAMIDES FOR THE TREATMENT OF CANCER HDAC5, HDAC1, HDAC4 KDM1A 57/4885MAOA 1064/4885GRIN2B 1272/4885
US-20240025853-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES NIT2, ARG1, CNPY2 KDM1A 801/4885MAOA 1104/4885GRIN2B 1290/4885
US-12077503-B2 Substituted cyclic amides and their use as herbicides NIT2, ARG1, CNPY2 KDM1A 801/4885MAOA 1104/4885GRIN2B 1290/4885
US-20250129079-A1 SALTS AND PROCESSES OF PREPARING A PI3K INHIBITOR PIK3CD, PIK3CA, PIK3CG KDM1A 1142/4885MAOA 4512/4885GRIN2B 1535/4885
US-20220024934-A1 SALTS AND PROCESSES OF PREPARING A PI3K INHIBITOR PIK3CD, PIK3CA, PIK3CG KDM1A 1142/4885MAOA 4512/4885GRIN2B 1535/4885
US-10961197-B2 Metal chelators for imaging, therapeutics, and bioanalysis TBCA, SLC39A3, TBL3 KDM1A 3024/4885MAOA 2049/4885GRIN2B 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.