Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922014 | 0.91 | POLB (0.41) | NPSR1L3MBTL1SYKPOLBMMP13 | |
| SCHEMBL30307663 | 0.81 | POLB (0.47) | NPSR1L3MBTL1SYKPOLBALDH1A1 | |
| SCHEMBL30878162 | 0.81 | POLB (0.47) | NPSR1L3MBTL1SYKPOLBALDH1A1 | |
| SCHEMBL2499502 | 0.81 | POLB (0.47) | NPSR1L3MBTL1SYKPOLBALDH1A1 | |
| SCHEMBL28380577 | 0.78 | HDAC3 (0.41) | L3MBTL1SYKPOLBALDH1A1ABCB1 | |
| SCHEMBL18256544 | 0.78 | ABCB1 (0.40) | L3MBTL1SYKPOLBALDH1A1ABCB1 | |
| SCHEMBL18248117 | 0.78 | ABCB1 (0.40) | L3MBTL1SYKPOLBALDH1A1ABCB1 | |
| SCHEMBL21447938 | 0.78 | ABCB1 (0.40) | L3MBTL1SYKPOLBALDH1A1ABCB1 | |
| SCHEMBL25203184 | 0.78 | POLB (0.45) | NPSR1L3MBTL1SYKPOLBALDH1A1 | |
| SCHEMBL19393967 | 0.78 | POLB (0.45) | NPSR1L3MBTL1SYKPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669095-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-06 | — | — | US | disclosed |