Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921972 | 0.91 | NPSR1 (0.44) | POLBNPSR1L3MBTL1SYKMMP13 | |
| SCHEMBL18922015 | 0.85 | POLB (0.44) | POLBNPSR1L3MBTL1SYKNTSR1 | |
| SCHEMBL30878162 | 0.83 | POLB (0.47) | POLBNPSR1L3MBTL1SYKABCB1 | |
| SCHEMBL30307663 | 0.83 | POLB (0.47) | POLBNPSR1L3MBTL1SYKABCB1 | |
| SCHEMBL2499502 | 0.83 | POLB (0.47) | POLBNPSR1L3MBTL1SYKABCB1 | |
| SCHEMBL23110219 | 0.81 | POLB (0.40) | POLBNPSR1L3MBTL1SYKCTSL | |
| SCHEMBL18921954 | 0.80 | POLB (0.42) | POLBL3MBTL1SYKNTSR1CTSL | |
| SCHEMBL17734155 | 0.80 | CA12 (0.31) | — | |
| SCHEMBL17734157 | 0.79 | — | — | |
| SCHEMBL23110306 | 0.79 | POLB (0.40) | POLBL3MBTL1SYKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669095-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-06 | — | — | US | disclosed |